Structures

Immunology  •  Adhesion  •  Virology  •  Matrix  •  Neuroscience




N15 TCR in complex with H57 Fab
PDB: 1NFD
EMBO J. 1998; 17: 10-26



Class 1:
N15 TCR bound to H2-Kb/VSV
Current Biology, 1998; 8: 409-412

Class 2:
D10 TCR bound to I-Ak/CA
(scD10 is a single chain construct Vß8.2-Vα2 with 15 residues linker in between)
PDB: 1D9K
Science, 1999; 286: 1913-1921


1) Left Panel:
CD8αα homodimer in complex with H-2Kb
PDB: 1BQH
Immunity, 1998, 9: 519-530
 
2) Right Panel:
CD4-D1D2 in complex with I-Ak
PDB: 1JL4
PNAS, 2001; 98: 10799-10804


A V-shaped ternary complex model with class II pMHC interacting with both TCR and CD4 molecules.
PNAS, 2001; 98: 10799-10804


Non-classic MHC molecule TL in complex with CD8αα homodimer PDB: 1NEZ
Immunity, 2003; 18: 205-215


CD8αβ heterodimer
PDB: 2ATP
Immunity, 2005; 23: 661-671

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